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Brand MD, Orr AL, Perevoshchikova IV, Quinlan CL

FIGURE 3 3.3.2 Insulin-like growth factor I-related proliferation and apoptosis Higher serum level of insulin-like growth factor I (IGF-I) has been associated with an increased risk of cancer by stimulating proliferation and suppressing apoptosis (Giovannucci et al., 2000